Amyloidosis is a rare disease that occurs when an abnormal protein, amyloid, builds up in the organs and interferes with normal function. Mayo Clinic expert on cardiac amyloidosis, Martha Grogan, M.D., discusses new treatment options in this video. https://mayocl.in/3dfwwZB | Mayo Clinic

Cardiac Amyloidosis Definition Cardiac amyloidosis is an infiltrative restrictive cardiomyopathy caused by deposition of misfolded amyloid fibrils in the myocardium, leading to stiff, noncompliant ventricles and progressive heart failure with preserved ejection fraction (HFpEF). Major Types Affecting the Heart 1--AL (Light Chain) Amyloidosis Derived from immunoglobulin light chains (κ or λ). Associated with plasma cell dyscrasias (e.g., multiple myeloma). Rapid progression; median survival witho