Researchers identified PGG, a pomegranate compound, as an amyloid disruptor that breaks down toxic transthyretin aggregates.

A research team at Kumamoto University has discovered that a natural compound found in pomegranate leaves and branches can ...

Transthyretin-mediated (ATTR) amyloidosis is a multisystem disease caused by the abnormal deposition of misfolded transthyretin protein as amyloid fibrils in various tissues. ATTR amyloidosis presents ...

Researchers have identified a natural compound from pomegranate leaves and branches that can directly dismantle the protein aggregates responsible for transthyretin amyloidosis.

This rare condition can’t be cured, but its symptoms can be treated. Take this assessment to learn what more you can do to manage the condition. Before you were diagnosed with transthyretin ...

A research team in Kumamoto University has discovered that a natural compound found in pomegranate leaves and branches can ...

Researchers identified a bioactive compound called PGG (1,2,3,4,6-penta-O-galloyl-β-D-glucose) from pomegranate (Punica granatum) leaf and branch extracts through plant library screening. Laboratory ...

WILMINGTON, Del.--(BUSINESS WIRE)-- Eplontersen has been granted Orphan Drug Designation (ODD) in the US by the Food and Drug Administration (FDA) for the treatment of transthyretin-mediated ...

Hereditary transthyretin amyloidosis (hATTR) is a rare inherited disorder that gets worse over time. It often affects the nerves, heart, liver, and kidneys, but it can also affect other organs.

While still considered a rare disease, transthyretin amyloid cardiomyopathy (ATTR-CM) is nevertheless emerging in more people than previously thought due to increased interest and improved access to ...

Credit: Alnylam. The approval for the ATTR-CM indication was supported by data from the HELIOS-B study. Treatment with vutrisiran led to a statistically significant reduction in the composite of ...