Upregulated expression of transcription factors promoting cone identity in late-stage retinal progenitors drives development ...

Every cell in our body contains the same DNA, yet liver cells are different from brain cells, and skin cells differ from muscle cells. What determines these differences? It all comes down to gene ...

Many of the body's processes slow down or falter as we get older, including tissue regeneration. In a new study, researchers detail a promising method to get this vital repair work back up to speed.

UCSF researchers identified 30 transcription factors that reverse age-related gene expression in fibroblasts. Using CRISPR to ...

DNA can be thought of as a vast library that stores all genetic information. Cells do not use this information all at once. Instead, they copy only the necessary parts into RNA, which is then used to ...

In a new study published in Cell Reports, researchers at the University of Freiburg detail how a disordered protein fragment connects two key stages of gene expression: transcription and RNA editing.

A newly discovered code within DNA -- coined 'spatial grammar' -- holds a key to understanding how gene activity is encoded in the human genome. This breakthrough finding revealed a long-postulated ...

An extraction-free kit enables gene expression analysis directly from hepatocyte lysates, delivering results in 75 minutes with sensitivity comparable to RNA purification.

During development, many crucial genes help organisms form properly. One of those genes is myogenic determination gene number 1 (MyoD), which can exert a powerful influence as a “genome organizer." It ...