The orchestration of T cell activation is central to immune defence and self-tolerance. Recent advances have revealed that T cells integrate signals from their antigen receptors alongside a network of ...

Conventional studies on stem cell fates are primarily focused on transcription factors, with the limited consideration for 3D genome architecture. The cohesin complex dynamically restructures ...

Gene regulation is far more predictable than previously believed, scientists conclude after developing the deep learning ...

In living cells, regulation of the electrochemical environment is supposed to be managed by ion channels—protein complexes that reside in cell membranes and assume definite shapes. So, it’s surprising ...

Critical proteins involved in animal stem cell regulation are much older than previously thought, predating the origin of animals that likely evolved more than 700 million years ago. This is the ...

The same cellular renewal that keeps our bodies healthy might also fuel the growth of cancer. A UC Merced biologist has found that the brain could hold the key to stopping it. Professor Néstor Oviedo, ...

Immunometabolism has emerged as a central hub linking infection, inflammation, cell death, and cancer. The metabolic state of cells profoundly shapes their ...

Gene regulation is far more predictable than previously believed, scientists conclude after developing deep learning model ...