An off-the-shelf immunotherapy for targeting solid tumors: Ready-to-use CAR-NKT cells show promise

A UCLA research team has identified the best design for a promising new type of immunotherapy that could be mass-produced to ...
EurekAlert!

UCLA scientists identify optimal design for off-the-shelf immunotherapy targeting solid tumors

A UCLA research team has identified the best design for a promising new type of immunotherapy that could be mass-produced to ...
Fierce Biotech

FDA signals tailored approach to ‘carefully shepherd’ CAR-T therapy for autoimmune diseases

While interested in CAR-T therapies’ potential to achieve durable, drug-free remission in serious autoimmune conditions, the ...
Hoodline

San Diego Labs Flip T Cell Kill Switches In High-Stakes Cancer Fight

For San Diego researchers and the wider immunotherapy community, the atlas functions as a practical roadmap. It does not ...
Medical Xpress

Engineered cell cross-talk unlocks CAR-T potential against glioblastoma

A team of researchers from the San Raffaele-Telethon Institute for Gene Therapy (SR-TIGET, Milan), led by Nadia Coltella and Luigi Naldini, has unveiled a powerful strategy to rejuvenate the ...
The American Journal of Managed Care

CAR T-Cell Therapy Holds Potential in SCLC, but Significant Barriers Remain

CAR T-cell therapy shows promise for SCLC, but significant barriers, such as tumor heterogeneity and immunosuppression, must be addressed. Identifying tumor-selective antigens like CDH17, GD2, and ...
News Medical

Universal CAR T cell therapy shows promise for aggressive T cell cancers

A new type of immunotherapy that targets aggressive blood cancers shows promising results alongside manageable side effects, according to the results of an international phase 1/2 clinical trial led ...
The University of Chicago Chronicle

New ‘plug-and-play’ cell design could revolutionize cancer immunotherapy

Researchers at the University of Chicago have developed a modular cancer immunotherapy that can be switched on, off or reprogramed to attack different cancers. Promising initial testing results, ...
News Medical

Study unveils powerful strategy to rejuvenate effectiveness of CAR T cell therapy against glioblastoma

A team of researchers from the San Raffaele-Telethon Institute for Gene Therapy (SR-TIGET, Milan), led by Nadia Coltella and Luigi Naldini, has unveiled a powerful strategy to rejuvenate the ...

A genetic blueprint for avoiding killer T cell exhaustion

A multi-institutional study led by researchers at UNC Lineberger Comprehensive Cancer Center, the Salk Institute for Biological Studies, and UC San Diego has uncovered new genetic rules that determine ...